Thiamyxins
WebOur goal is to generate and develop hit and lead compounds, which are eventually transferred to the clinic. We have successfully established an in-house strain collection containing more than 10.000 unique myxobacterial … Web29 Aug 2024 · The Thiamyxins showed potent inhibition of different RNA-viruses as analysed in cell culture models of corona, zika and dengue virus infection.
Thiamyxins
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Web20 Mar 2024 · Discovery of two novel classes of natural products with activity against RNA viruses Web8 Oct 2024 · These thiazole- and thiazoline-containing cyclic depsipeptides are produced by a nonribosomal peptide synthetase-polyketide synthase hybrid biosynthetic gene cluster, …
Web22 Mar 2024 · HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in cooperation with Saarland University. The researchers have now succeeded in isolating … Web22 Mar 2024 · Discovery of two novel classes of natural products with activity against RNA viruses. The COVID-19 pandemic has dramatically demonstrated that the development of effective agents against viral pathogens is of great importance for global health. Although effective vaccines are available for many viral diseases, there is an urgent need for new …
WebThiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors (Mueller) @helmholtz_hips @ChantalBader #openaccess thanks to #projektDEAL https ... WebThiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors. P. Haack, K. Harmrolfs, C. Bader, R. Garcia, A. Gunesch, S. Haid, A. Popoff, A. Voltz, H. Kim, R. …
Web20 Mar 2024 · HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in cooperation with Saarland University. The researchers have now succeeded in isolating …
Web21 Mar 2024 · Detailed description. This factor is mainly used to control the therapeutic process of infections with HIV, cytomegaly viruses, hepatitis A viruses and hepatitis B … going ostrichWebThiamyxins: Structure and Biosynthesis of Myxobacterial RNA‐Virus Inhibitors: Angewandte Chemie International Edition: 1 hour: save: Vibration‐Regulated Multi‐State Long‐Lived … hazards cyclesWeb1 Sep 2024 · The Thiamyxins showed potent inhibition of different RNA-viruses as analysed in cell culture models of corona, zika and dengue virus infection. Their potency up to a … going our wayWeb21 Mar 2024 · The COVID-19 pandemic has dramatically demonstrated that the development of effective agents against viral pathogens is of great importance for global … hazards construction siteWebThis publication has not been reviewed yet. rating distribution. average user rating 0.0 out of 5.0 based on 0 reviews going our way 2WebThe thiamyxins were found to exhibit promising antiviral activity against three different RNA viruses. Abstract During our search for novel myxobacterial natural products, we … going out 1981WebThe thiamyxins show potent inhibition of RNA-viruses in cell culture models of corona, zika and dengue virus infection and their potency up to a half maximal inhibitory concentration of 560 nM combined with milder cytotoxic effects on human cell lines indicate a potential for further development of the thiamxins. During our search for novel myxobacterial natural … hazards defined by industrial hygiene