WebSerum free light chain (SFLC) quantification aids in diagnosing multiple myeloma and determining prognosis. 3 Bone marrow evaluation is essential for diagnosis. 2 Further testing can include multiparameter flow cytometry and plasma cell fluorescence in situ hybridization (FISH) to further determine prognosis and cytogenetic studies to identify … WebDec 12, 2024 · Multiple myeloma (MM) is typically characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The plasma cells proliferate in the bone marrow and can result in extensive skeletal destruction with osteolytic lesions, osteopenia, and/or pathologic fractures.
Serum Free Light Chains - Testing.com
WebThe serum free light chain assay (brand name Freelite®) is used for diagnosis and monitoring of myeloma. Immunoglobulin proteins are made up of two kinds of molecules, … The International Myeloma Foundation medical and editorial content team. … WebNov 5, 2024 · Background: In addition to serum protein electrophoresis (SPEP) and serum immunofixation (IFE), measurement of serum free light chains (FLC) has become the … schwan plural
Cardiac amyloidosis: A survey of current awareness, diagnostic ...
WebJan 1, 2005 · A polyclonal gammopathy is characterized by a broad diffuse band with one or more heavy chains and kappa and lambda light chains. 7 Once a monoclonal … WebSPEP provides the highest-quality access hardware to OEMs and distributors across the globe. Our innovative parts are engineered to reduce costs and improve performance for … Webin detecting some M-proteins that are free light chains by itself without the heavy chain. It is more sensitive to detect monoclonal free light chains than urine immunofixation, and may be used instead of the UPEP to screen for BenceJones - protein.4 . It is important to understand how SPEP works and what may cause false-positive findings. practice saaq knowledge test