WebEgr-1 is a member of the early growth response gene family like the c-fos and c-jun protooncogenes. Egr-1 expression is induced in many types of cells by various mitogenic stimuli or malignant transformation signals. The Egr-1 promoter is known to be transiently activated by ionizing radiation. WebApr 4, 2024 · early growth response protein 1, Krox-24 nuclear protein, nerve growth factor-induced protein A, transcription factor Zif268, zinc finger protein Krox-24. GeneRIFs: Gene References Into Functions. The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
EGR1 Gene - GeneCards EGR1 Protein EGR1 Antibody
WebApr 8, 2024 · The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) and extracellular vesicles (EVs) in the patient's body fluid. Liquid biopsy has important roles in translational research. But its clinical utility is still under investigation. … EGR-1 (Early growth response protein 1) also known as ZNF268 (zinc finger protein 268) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24, TIS8, and ZENK. It was originally discovered in mice. See more The protein encoded by this gene belongs to the EGR family of Cys2His2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for … See more The DNA-binding domain of EGR-1 consists of three zinc finger domains of the Cys2His2 type. The amino acid structure of the EGR-1 zinc … See more EGR-1 has been shown to interact with: • CEBPB, • CREB-binding protein, • EP300, • NAB1, See more • Zif+268+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • FactorBook Egr-1 See more EGR-1 binds the DNA sequence 5'-GCG TGG GCG-3' (and similar ones like 5'-GCG GGG GCG-3'). The f1 position 6 binds the 5' G (the first base count from the left); the f1 position 3 to the second base (C); f1 position -1 binds to the third position (G); f2 … See more • Zinc finger See more • Heath RG (March 1975). "Brain function and behavior. I. Emotion and sensory phenomena in psychotic patients and in experimental … See more how can you charge a battery
Involvement of miR-20a in Promoting Gastric Cancer …
Webthe VEGF gene (1). Another transcription factor that is upregulated by hypoxia is early growth response protein 1 (EGR1). EGR1 is part of a family of immediate early genes … WebMar 13, 2024 · Early growth response factor 1 (Egr-1) is an early gene, belonging to the EGR family that codes for a Cys 2-His 2 zinc finger protein . It is located on human … WebKeywords: gastric cancer; miR-20a; early growth response 2; carcinogenesis; chemoresistance 1. Introduction Gastric cancer (GC) is one of the most common cancers … how many people remain single